A Novel Ayurvedic treatment - Arthrothermia® for Osteoarthritis
Abstract
Purpose: The purpose of this study was to report promising data revealed by a novel Ayurvedic treatment; Arthothermia® for patients with knee osteoarthritis (OA). Method: We enrolled 30 patients with OA who received Arthothermia® treatment. The Knee injury and Osteoarthritis Outcome Score (KOOS) was used to evaluate the treatment outcome. The five subscales of KOOS: Pain, Other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL) were scored separately. The KOOS data was calculated for the 30 patients before and after Arthothermia® treatment. Results: The KOOS before Arthothermia® ranged from 3.37 to 31.3. The KOOS was significantly improved after Arthothermia® and it ranged from 83.67 to 98.53. The difference in KOOS between before and after Arthothermia® treatment was calculated for the 30 patients as a group (unpaired t-test) as well as for each patient individually (paired t-test). The difference in KOOS was highly significant (p<0.0001) for both; unpaired and paired t-test analysis. Conclusion: The present study documented that the “Arthothermia®” – a unique Ayurveda treatment approach (combination of alkaline cautery and indirect micro thermal cautery) brought significant changes in KOOS in the OA patients in very short time duration. The promising data hold a ray of hope for better management of OA and needs wide explorations to bring magnificent outcome for patients suffering with OA.
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References
Yadav, Rohit; Verma, Ajay Kumar1; Uppal, Arjun; Chahar, Hemant Singh; Patel, Jaydeep; Pal, Chandra Prakash. Prevalence of Primary Knee Osteoarthritis in the Urban and Rural Population in India. Indian Journal of Rheumatology September 2022; 17(3): p. 239-243; doi: 10.4103/injr.injr_337_20
Kouraki, A., Bast, T., Ferguson, E. et al. The association of socio-economic and psychological factors with limitations in day-to-day activity over 7 years in newly diagnosed osteoarthritis patients. Sci Rep 2022; doi: 10.1038/s41598-022-04781-3
A. Singh, S. Das, A. Chopra, D. Danda, B.J. Paul, L. March, A.J. Mathew, P. Shenoy, C. Gotay, A.J. Palmer, B. Antony. Burden of osteoarthritis in India and its states, 1990–2019: findings from the Global Burden of disease study 2019. Osteoarthritis and Cartilage 2022; 30:8: p. 1070-1078; doi: 10.1016/j.joca.2022.05.004
Buelt A, Narducci DM. Osteoarthritis Management: Updated Guidelines from the American College of Rheumatology and Arthritis Foundation. Am Fam Physician. 15 January 202; 103(2): p.120-121. PMID: 33448759.
Brahmanand Tripathi. Caraksamhita of Agnivesh elaborated by Caraka & Drdhabala, Edited with Caraka chandrika hindi commentary, Varanasi: Chaukhamba Sanskrit Sanshthan; 2015.Sutra Sthana, Arthedashmahamuliya adhyaya, verse 20:26: p. 565.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:1: p. 45.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Agnikarmavidhi adhyaya, Verse 12:1: p. 50.
Grässel, S. The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology. Arthritis Res Ther; 2014. 16:485; doi :10.1186/s13075-014-0485-1
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Yantravidhi adhyaya, Verse 8:15: p. 39.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Yantravidhi adhyaya, Verse 8:16: p. 39.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:11-15: p. 47-48.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:6: p. 46.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:7-8: p. 46.
Brahmanand Tripathi. Astanga hrdayam of Srimadvagbhata, Edited with Nirmala hindi commentary. Varanasi: Chaukhamba Sanskrit Sanshthan; 2014. Sutra Sthana, Kshar-Agnikarmavidhi adhyaya, Verse 30:41: p. 333.
Neha Uniyal, Pankaj Kumar Sharma, Sunil Gupta, & Devesh Shukla. A Review on Agnikarma- A Boon for Pain Management and its Probable Mode of Action. International Journal of Ayurveda and Pharma Research, 2022; 10(3): p.140-144.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Agnikarmavidhi adhyaya, Verse 12:10: p. 52.
Prerak Shah, Dr. Dhruti Kagrana. Effect of Arthrothermia on Narrowing of AP Diameter of Lumber Discs – A case report. International Journal of Scientific Research, August 2023; 12 (8): P. 54-55.
Brahmanand Tripathi. Astanga hrdayam of Srimadvagbhata, Edited with Nirmala hindi commentary. Varanasi: Chaukhamba Sanskrit Sanshthan; 2014. Sutra Sthana, Kshar-Agnikarmavidhi adhyaya, Verse 30:1-2: p. 328.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:28: p. 49.
Brahmanand Tripathi. Astanga hrdayam of Srimadvagbhata, Edited with Nirmala hindi commentary. Varanasi: Chaukhamba Sanskrit Sanshthan; 2014. Sutra Sthana, Kshar-Agnikarmavidhi adhyaya, Verse 30:8-21: p. 329-330.
Brahmanand Tripathi. Astanga hrdayam of Srimadvagbhata, Edited with Nirmala hindi commentary. Varanasi: Chaukhamba Sanskrit Sanshthan; 2014. Sutra Sthana, Kshar-Agnikarmavidhi adhyaya, Verse 30:22-23: p. 330.
Brahmanand Tripathi. Astanga hrdayam of Srimadvagbhata, Edited with Nirmala hindi commentary. Varanasi: Chaukhamba Sanskrit Sanshthan; 2014. Sutra Sthana, Kshar-Agnikarmavidhi adhyaya, Verse 30:28: p. 331.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:3: p. 45.
Tiong WH, Kelly EJ. Salicylic acid burn induced by wart remover: a report of two cases. Burns. 2009 Feb;35(1):139-40. doi: 10.1016/j.burns.2007.10.013. Epub 2008 Mar 28. PMID: 18375067.
Claros-Chacaltana FDY, Kobashigawa KK, Padua IRM, Valdetaro GP, Aldrovani M, Laus JL. Corneal angiogenesis based on different protocols of alkaline cauterization in murine models. Acta Cir Bras. August 2017;32(8):607-616. doi: 10.1590/s0102-865020170080000002. PMID: 28902936.
Anwar A, Rafiq Z, us Salam S. Comparison of efficacy of electrocautery vs. cryotherapy in the treatment viral warts. J Fatima Jinnah Med Univ [Internet]. 7Apr.2022 [cited 18Dec.2023];15(4): p.177-180.
Mahapatra A, Srinivasan A, Sujithra R, Bhat RP. Management of internal hemorrhoids by Kshara Karma: An educational case report. J Ayurveda Integr Med. 3 July 2012;3(3): p.115-118; doi: 10.4103/0975-9476.100169. PMID: 23125506; PMCID: PMC3487235.
Maheshkumar Bharat Raut. Conceptual study on Agnikarma in Ayurveda. Journal of Ayurveda and Integrated Medical Sciences. 2023; 8(5), p. 150 - 153.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Agnikarmavidhi adhyaya, Verse 12:4: p. 51.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Ksharpakvidhi adhyaya, Verse 11:7: p. 46.
Sanjay A. Dhurve. A Critical Conceptual Study on Agnikarma. International Journal of Science and Research. July 2022; 11(7): p. 1677-1681.
Kaviraj Ambikadutta Shastri. Sushrutsamhita of Maharshi-Sushrut, Edited with Ayurveda-Tattva-Sandipika. Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Agnikarmavidhi adhyaya, Verse 12:3: p. 50.
Moreira, Cristiane & Amaral, Eliana. Use of Electrocautery for Coagulation and Wound Complications in Caesarean Sections. The Scientific World Journal. 2014.
Jethava NG, Dudhamal TS, Gupta SK. Role of Agnikarma in Sandhigata Vata (osteoarthritis of knee joint). Ayu. Jan-Mar 2015; 36(1): p. 23-8; doi: 10.4103/0974-8520.169017
Roos EM, Lohmander LS. The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis. Health Qual Life Outcomes. November 2003; 1:64; doi: 10.1186/1477-7525-1-64.
Pal CP, Singh P, Chaturvedi S, Pruthi KK, Vij A. Epidemiology of knee osteoarthritis in India and related factors. Indian J Orthop. September 2016; 50(5): p.518-522. doi: 10.4103/0019-5413.189608.
Jaimie D Steinmetz. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Rheumatology.2023; 5(9): p.508-522; doi: 10.1016/S2665-9913(23)00163-7
Singh A, Das S, Chopra A, Danda D, Paul BJ, March L, Mathew AJ, Shenoy P, Gotay C, Palmer AJ, Antony B. Burden of osteoarthritis in India and its states, 1990-2019: findings from the Global Burden of disease study 2019. Osteoarthritis Cartilage. August 2022; 30(8): p.1070-1078.
Mishra P, Singh U, Pandey CM, Mishra P, Pandey G. Application of student's t-test, analysis of variance, and covariance. Ann Card Anaesth. October – December 2019; 22(4): p.407-411.
Ewa M. Roos, PT, MSc, Harald P. Roos, MD, PhD, L. Stefan Lohmander, MD, PhD, Charlotte Ekdahl, PhD, PT, Bruce D. Beynnon, PhD. Knee Injury and Osteoarthritis Outcome Score (KOOS)—Development of a Self-Administered Outcome Measure. Journal of Orthopaedic & Sports Physical Therapy. 1998; 28(2) p.88-96; doi: 10.2519/jospt.1998.28.2.88
M. Salavati, B. Akhbari, F. Mohammadi, M. Mazaheri, M. Khorrami. Knee injury and Osteoarthritis Outcome Score (KOOS); reliability and validity in competitive athletes after anterior cruciate ligament reconstruction. Osteoarthritis and Cartilage. 2011; 19(4): p. 406-410,, doi.org/10.1016/j.joca.2011.01.010
Nawaf Rawaf Alfahad, Mohammed Ali Alruwaili, & Hadeel Fahad Alothaim. Evaluation of Knee Injury and Osteoarthritis Outcome Scale (KOOS). International Journal of Recent Innovations in Medicine and Clinical Research. 2022; 4(2): p.10–17.
Brahmanand Tripathi. Carak samhita of Agnivesh elaborated by Caraka & Drdhabala, Edited with Caraka chandrika hindi commentary, Varanasi: Chaukhamba Sanskrit Sanshthan; 2015.Chikitsa Sthana, Vatvyadhichikitsa adhyaya, verse 28:32-33-35-37: p. 942.
Brahmanand Tripathi. Caraksamhita of Agnivesh elaborated by Caraka & Drdhabala, Edited with Caraka chandrika hindi commentary, Varanasi: Chaukhamba Sanskrit Sanshthan; 2015. Sutra Sthana, Dirghamjivitiya adhyaya, verse 1:59: p. 32.
K. Sembulingam, Prema Sembulingam. Structure of Skeletal Muscle. Essentials of Medical Physiology, Edition 5, Jaypee Bros. Medical Publishers (P) Ltd.: New Delhi. 2010, p. 169.
K. Sembulingam, Prema Sembulingam. Changes during muscular contraction,. Essentials of Medical Physiology, Edition 5, Jaypee Bros. Medical Publishers (P) Ltd.: New Delhi. 2010, p. 177
K. Sembulingam, Prema Sembulingam. Neuro-muscular Junction.Essentials of Medical Physiology, Edition 5, Jaypee Bros. Medical Publishers (P) Ltd.: New Delhi. 2010, p. 189.
K. Sembulingam, Prema Sembulingam. Smooth Muscle. Essentials of Medical Physiology, Edition 5, Jaypee Bros. Medical Publishers (P) Ltd.: New Delhi. 2010, p. 193.
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