Clinical Evaluation of Kofsap-Sf Cough Syrup for Persistent Cough Relief: A Pilot Study

  • Sibi Narayanan Manager, Research & Development Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
  • Anu Joy Research Officer, Research & Development Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
  • Maneesha KS Jr. Officer, Research & Development Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
  • Sreedevi AP Research Trainee, Research & Development Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
  • Reeshma CR Jr. Chemist, Research & Development Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
  • Adithya Peethambara Panicker AGM-M&I, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
Keywords: Persistent cough, herbal medicine, sugar-free syrup, Kofsap-SF, respiratory health

Abstract

Introduction: Persistent cough significantly impacts patient well-being. Traditional cough syrups often contain sugar, which can be unsuitable for diabetic or health-conscious individuals.

Objective: To evaluate the clinical efficacy and safety of Kofsap-SF, a sugar-free herbal syrup, in relieving persistent cough and improving quality of life.

Methods: An open-label, single-arm pilot study was conducted with 30 participants aged 35–60 years diagnosed with persistent cough. Participants received 10 ml of Kofsap-SF syrup three times daily for 2–4 weeks. Symptom severity and quality of life were assessed using the Cough-Specific Quality of Life Questionnaire (CQLQ).

Results: The average symptom score decreased from 14 at baseline to 8 by Week 2 and 4 by Week 4. Quality of life scores improved from 10 to 4. 63% of participants showed significant symptom relief by Week 2; the remainder responded by Week 4. No adverse effects were reported.

Conclusion: Kofsap-SF is an effective sugar-free herbal remedy for persistent cough, demonstrating symptom reduction and improved quality of life. Larger randomized trials are warranted.

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CITATION
DOI: 10.21760/jaims.10.7.5
Published: 2025-07-25
How to Cite
1.
Sibi Narayanan, Anu Joy, Maneesha KS, Sreedevi AP, Reeshma CR, Adithya Peethambara Panicker. Clinical Evaluation of Kofsap-Sf Cough Syrup for Persistent Cough Relief: A Pilot Study. J Ayurveda Integr Med Sci [Internet]. 2025Jul.25 [cited 2025Aug.13];10(7):33 -9. Available from: https://jaims.in/jaims/article/view/4353
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Original Article