Diabetes Care with Reversal Therapy: A Case Study on Remission of Type II Diabetes with Resolution of Grade II Fatty Liver
Abstract
Background: Type II Diabetes Mellitus (T2DM) often coexists with non-alcoholic fatty liver disease (NAFLD), leading to compounded metabolic and cardiovascular risks. While conventional therapy emphasizes medication-based management, integrative and holistic therapies offer potential for disease reversal. This case study evaluates the effect of Panchsutri Reversal Therapy a multidimensional Ayurvedic lifestyle approach on T2DM and Grade II fatty liver.
Methods: A 55-year-old male with a 6-year history of T2DM and imaging-confirmed Grade II fatty liver underwent a 90-day integrative therapy protocol involving Panchakarma (detoxification), an 800–1000 calorie diet, continuous monitoring, progressive tapering of medications, daily physical activity, and stress management. Baseline and follow-up data were collected.
Results: Post-treatment, the patient shows normalized glucose tolerance test (GTT), fasting blood glucose reduction from 130.42 to 110 mg/dL, postprandial blood glucose reduction from 188 to 140 mg/dL, and HbA1c improvement from 7.2% to 6.2%. Imaging revealed resolution of fatty liver from Grade II to no significant anomaly. The patient also experienced 100% relief from right gluteal pain, neuropathic symptoms, itching, stomatitis, and gastrointestinal complaints. Weight reduced from 75.7 kg to 69 kg, BMI from 26.2 to 23.8, and systolic/diastolic blood pressure improved from 138/87 mmHg to 113/70 mmHg. All Allopathic medications were discontinued.
Conclusions: This holistic Reversal Therapy led to diabetes remission and reversal of fatty liver in this patient. These results highlight the potential of integrative, non-drug therapies for managing metabolic diseases.
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References
American Diabetes Association. Standards of Medical Care in Diabetes—2024. Diabetes Care. 2024;47(Supplement_1):S1-S290.
Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73–84.
Targher G, Day CP, Bonora E. Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. N Engl J Med. 2010;363(14):1341–50.
Bailey CJ. The challenge of managing coexistent type 2 diabetes and non-alcoholic fatty liver disease. Diabetologia. 2020;63(10):2057–66.
Lean MEJ, Leslie WS, Barnes AC, et al. Durability of a primary care–led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-lab
Bhalerao S, Patil K el, cluster-randomised trial. Lancet Diabetes Endocrinol. 2019;7(5):344–55.
Thakkar S. Ayurvedic management of diabetes mellitus: An evidence-based holistic approach. J Ayurveda Integr Med. 2012;3(2):61–70.
Thatte UM, Dahanukar SA. Reversal of type 2 diabetes mellitus through Panchakarma: a case series. J Ayurveda Integr Med. 2015;6(3):234–40.
Hallberg SJ, Gershuni VM, Hazbun TL, Athinarayanan SJ. Reversing Type 2 Diabetes: A Narrative Review of the Evidence. Nutrients. 2019;11(4):766.
Taylor R. Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause. Diabetologia. 2008;51(10):1781–9.
Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non‐alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, the American College of Gastroenterology, and the American Gastroenterological Association. Hepatology. 2012;55(6):2005–23.
Bouchonville MF, Armamento-Villareal R. Weight loss and diabetes reversal: What is the evidence? Curr Diab Rep. 2021;21(2):6.
