Efficacy of Single Drug Therapy in the management of Subclinical Hypothyroidism: A Case Series analysis using Ayurvedic approach

Abstract

Subclinical hypothyroidism (SCH) is characterized by elevated thyroid-stimulating hormone (TSH) levels with normal free thyroxine (T4) levels. Herbal formulations used in Ayurvedic medicine offer a comprehensive strategy that may be beneficial to controlling symptoms than conventional treatment, which usually concentrate on hormone replacement. This case series aims to determine the effectiveness of single drug therapy in treating Subclinical Hypothyroidism, with a focus toward evaluating biochemical markers and clinical outcomes which is need of the hour. A total of 8 patients diagnosed with subclinical hypothyroidism were treated with Shigru Patra Churna tablet over 42 days. Patient information was gathered both before and after treatment, including symptoms, TSH levels, and measures of quality of life. Preliminary findings suggest that patients experienced symptomatic relief along with normalization of thyroid function test (TFT) results. The use of Shigru led to notable improvements in clinical symptoms, with TSH levels returning to normal in 7 out of 8 cases. This case series offers encouraging evidence that single drug therapy in Ayurveda can serve as an effective treatment for subclinical hypothyroidism. Additional studies with larger sample sizes and controlled designs are needed to confirm these results and better understand the underlying mechanisms.