Therapeutic role of vegetables in Respiratory Diseases – A critical review from Ayurvedic classics.
Abstract
The concept of Pathya (wholesome diet) is an unique contribution of Ayurveda, which plays an important role in prevention and management of many diseases. “Shakavarga”, a category under dietetics in classical texts of Ayurveda enlisted different vegetables with their properties and indications in different disease conditions. These vegetables can be prescribed as Pathya (wholesome diet) in clinical practice. In the present review, plants described under Shakavarga, indicated as Pathya in different diseases related to Pranavaha Srotas (Respiratory system) were compiled from 15 different Ayurvedic classical texts. Critical analysis of the compiled data reveals that out of 332 vegetables described under Shakavarga, 44 are indicated in respiratory disease like Shvasa (Dyspnoea/Asthma), Kasa (Cough), Peenasa (Chronic rhinitis) and Hikka (Hiccup). Among them, botanical identity of 42 classical plants has been established and maximum number of vegetables belongs to the family cucurbitaceae (10) followed by solanaceae (4). Some of these vegetables have been reported for their various pharmacological activities related to prevention and management of diseases related to Pranavaha Srotas (Respiratory system). These vegetables are reported for their anti-inflammatory (16), antioxidant (14), anti-allergic (6) and antitussive (3) activities. The observed result may be helpful in use of vegetables as Pathya (wholesome diet) and planning further scientific studies about the efficacy of these plants on prevention as well as management of respiratory diseases.
Downloads
References
Agnivesa, Caraka Samhita, with Ayurveda-Dipika Commentary of Cakrapanidatta by Vaidya Jadavji Trikamji Acharya, Editor. Chowkhamba Surbharati Prakashan, Varanasi, Reprint edition 2009:181.
Lolimbaraj. Vaidya jeevanam, Commented by Shri Kalika charan Pandeya and Shri Brahmashankara Shastri: Jaya Krishna Das Hari Das Gupta Press, India. 1947 chapter 1/10.
Halsted CH. Clinical nutrition education--relevance and role models. Am J Clin Nutr. 1998 Feb;67(2):192-6.
Vaidya Yadavaji Trikamji, Charaka Samhita of Agnivesha with Ayurveda dipika commentary, reprint edition ; Chaukamba Surabharat prakashan Varanasi, 2013:533.
P.V.Sharma; Charaka Samhita Vol.I, reprint edition (English); Varanasi, Chaukamba orientalia, 2008:329-333
Osler M, Tjønneland A, Suntum M, Thomsen BL, Stripp C, et al. (2002) Does the association between smoking status and selected healthy foods depend on gender? A population-based study of 54 417 middle-aged Danes. Eur J Clin Nutr 56: 57-63.
Toraldo DM, Nuccio FD, Scoditti E (2013) Systemic Inflammation in Chronic Obstructive Pulmonary Disease: May Diet Play a Therapeutic Role? J Aller Ther S2: 005. doi:10.4172/2155-6121.S2-005
Romieu I, Nutrition and lung health. Int J Tuberc Lung Dis. 2005 Apr;9(4):362-74.
Raghavendra Naik, Sneha D Borkar, R N Acharya, Role of Classical Vegetables of Ayurveda in the Prevention and Management of Cardiovascular Diseases-A Review. Research & Reviews: Journal of Food Science and Technology. 2015; 4(3):1-13
Raghavendra Naik, Sneha D Borkar, R N Acharya, Prevention And Management Of Diabetes Mellitus Through Classical Vegetables Of Ayurveda – A Critical Review, J Res Educ Indian Med, Vol. XXI 2015 doi:10.5455/JREIM.82
Raghavendra Naik, Sneha D Borkar, R N Acharya, Ayurvedic shaka dravyas (vegetables) and their role in prevention and management of dermatological disorders: a critical review, J of Ayurveda and Hol Med (JAHM).2015;3(6):68-89
Raghavendra Naik, Mital Buha, Rabinarayan Acharya, Sneha D Borkar, Role of Vegetables (Shaka Dravyas) in Prevention and Management of Gastro - Intestinal Tract Diseases: A Critical Review, J. res. tradit. medicine | Jul - Aug 2016 | Volume 2 | Issue 4
Vaidya Yadavaji Trikamji, Charaka Samhita of Agnivesha with Ayurveda dipika commentary, 2013 edition ; Chaukamba Surabharat Prakashan Varanasi, Sutrasthana 28.
Susruta samhita of susruta commented by dalhanacarya and sri gayadasacarya ,edited by vaidya jadavji trikamji acarya and narayan ram acarya ‘kavyatirth’, chowkhamba krishnadas academy, Varanasi, reprint,2004:230-236.
Ashtanga samgraha, by kaviraj atrideva gupta ,chowkhamba krishnadas academy, Varanasi ,revised 2005:71-75.
Acharya Vagbhata, Ashtanga Hridaya, Sutra Sthana 1/20 Brahmananda Tripathi, nirmala Hindi Vyakhya, Chaukhamba Sanskrita Pratishthn, Delhi, 2007:16
Dhanvantari Nighantu, Edited by Acharya P V Sharma, chaukhamba orientalia, Varanasi, reprint edition, Chaukhamba Orientalia, Varanasi, reprint edition 2008
Shodhal Nighantu, Edited by P V Sharma, Oriental Institute Baroda, 1978.
Madhava Dravyaguna, edited by P V Sharma, chaukhamba vidya bhavan , Varanasi, 1st edition 1973:51-57.
Madana pala Nighantu, Edited by Hariprasad Tripathi, Chakhambha Krisnadasa Academy, Varanasi, 1st edition 2009:167-185.
Kaiyadeva nighantu by prof. P V Sharma & Dr. Guruprasda Sharma, Chaukhamba orientalia Varanasi, 2nd edition 2006:65- 160.
Bhavaprakasha nighantu by Sri Bhavamisra, commented by Prof. K C Chunekar, Edited by Lt. Dr G S Pandey, Chaukambha bharati academy Varanasi, Revised and enlarged edition, 2010: 650-690
Raja Nighantu of Pandit Narahari, edited by Indradeva Tripathi, Chowkhamba Krisnadasa Academy, Varanasi, 5th Edition, 2010:190-231
Priya nighantu by Prof P V Sharma Chaukhamba sura bharati prakashan Varanasi, Edition 2004:163- 177.
Guna Ratnamala, edited by K P Pandey & A N Singh, Chaukambha Sanskrit Bhavan Varanasi, first edition 2006:418-465
Dravyaguna sangraha of Chakrapanidatta by vaidya Chandrakant sonare,chaukhamba orientalia, Varanasi, reprint edition 2006:73-106
Malabhatta, Dravyagunashatashloki, Shaka varga/39-49:6-7.
Vaidya Yadavaji Trikamji, Charaka Samhita of Agnivesha with Ayurveda dipika commentary, reprint edition ; Chaukamba Surabharat prakashan Varanasi, 2013:539
de Torres JP, Cordoba-Lanus E, Lo´pez-Aguilar C, et al. C-reactive protein levels and clinically important predictive outcomes in stable COPD patients. Eur Respir J 2006; 27: 902–907.
Pinto-Plata VM, Müllerova H, Toso JF, Feudjo-Tepie M, Soriano JB, Vessey RS, Celli BR.Thorax. C-reactive protein in patients with COPD, control smokers and non-smokers. 2006 Jan;61(1):23-8. Epub 2005 Sep 2.
Fabbri LM, Rabe KF (2007) From COPD to chronic systemic inflammatory syndrome? Lancet 370: 797-799.
Broekhuizen R, Wouters EF, Creutzberg EC, Schols AM (2006) Raised CRP levels mark metabolic and functional impairment in advanced COPD. Thorax 61: 17-22.
Nataraj Loganayaki, N Suganya, S Manian, Evaluation of edible flowers of agathi (S grandiflora L. Fabaceae) for in vivo anti-inflammatory and analgesic, and in vitro antioxidant potential Food Science and Biotechnology, April 2012, Volume 21, Issue 2:509-517
Saha S, Guria T, Singha T, Maity TK., Evaluation of Analgesic and Anti-Inflammatory Activity of Chloroform and Methanol Extracts of Centella asiatica Linn. ISRN Pharmacol. 2013 Nov 21;2013:789-613.
Prashanta Kr. Deb, Ranjib Ghosh, Raja Chakraverty, Rajkumar Debnath et al., Phytochemical and Pharmacological Evaluation of Fruits of Solanum indicum Linn. Int. J. Pharm. Sci. Rev. Res., Mar – Apr 2014, 25(2)
Mathur Abhishek , Gupta Vinay, Verma Satish K.et al,Anti-Inflammatory Activity of Different Fractions of Leucas Cephalotes Leaves Extract, IJCPR Feb –Apr 2011; 2(1);28-32
Ravi V, Saleem TSM, Patel SS1, Raamamurthy J, Gauthaman K, Anti-Inflammatory Effect of Methanolic Extract of Solanum nigrum Linn Berries, International Journal of Applied Research in Natural Products Vol. 2(2):33-36
M Ullah, Mir Showkat, Nazim Uddin Ahmed et al., Evaluation of Momordica charantia fruit extract for analgesic and anti-inflammatory activities using in vivo assay, Research journal of medicinal plants 2012:1-9
Ilango K, Maharajan G, Narasimhan, S. Analgesic and Anti-inflammatory Activities of Momordica dioica Fruit Pulp. Natural product sciences. 2003, 9(4):210-212.
Sadique J, Chandra T, Thenmozhi V, Elango V. Biochemical modes of action of C. occidentalis and Cardiospermum halicacabum in inflammation. J Ethnopharmacol. 1987; 19(2):201-12.
K. Binny, Sunil Kumar G, D. Thomas, Journal of Basic and Clinical Pharmacy, 2010.
Laxmi Ahirwal, Siddhartha Singh, Vandana Bharti and Archana Mehta, Immunosuppressive Effect Of Swertia chirata Buch Ham. on Swiss Albino Mice, International Journal of Pharmaceutical Sciences and Research, 2013; Vol. 4(12): 4763-4768.
Jagan Rao N, Jayashree T, Mallikarjuna Rao B et al., Evaluation of the anti-nociceptive and anti-inflammatory activity of the petroleum ether extract of Portulaca oleracea, Journal of clinical and diagnostic research 6(2);226-230
Nagar, Anil; Shukla, Alok Kumar; Bigoniya, Papiya, Anti-inflammatory potential of Spinacia oleracea leaf extract., Journal of Natural Pharmaceuticals . Apr2011, Vol. 2 Issue 2:80-87.
M. Badrul Alam, M. Sarowar Hossain, N. Sultana Chowdhury, M. Asadujjaman, Ronok Zahan, Antioxidant, Anti-inflammatory and Anti-pyretic Activities of Trichosanthes dioica Roxb. Fruits, Journal of Pharmacology and Toxicology, 2011, Volume: 6, Issue: 5; 440-453
Armando Ciiceresa’b, Amarillis Saraviab, Sofia Rizzoa, Lorena Zabalaa, et al.,Pharmacologic properties of Moringa oleifera: Screening for antispasmodic, anti inflammatory and diuretic activity, Journal of Ethnop~rmaco~ogy, 36 (1992) 233-237
Santosh.S.Bhujbal, Sohan.S.Chitlange, AnupamaA.Suralkar, Devanand.B.Shinde and Manohar J. Patil Anti- inflammatory activity of an isolated flavonoid fraction from Celosia argentea Linn., Journal of Medicinal Plants Research Vol. 2(3):052-054
Singh B, Sharma RA. Anti-inflammatory and antimicrobial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees. Phytomedicine. 2013 Mar 15;20(5):441-5
McKeever TM, Scrivener S, Broadfield E, Jones Z, Britton J, et al. (2002) Prospective study of diet and decline in lung function in a general population. Am J Respir Crit Care Med 165: 1299-1303.
Britton JR, Pavord ID, Richards KA, Knox AJ, et al. (1995) Dietary antioxidant vitamin intake and lung function in the general population. Am J Respir Crit Care Med 151: 1383-1387.
Grievink L, Smit HA, Ocké MC, van ‘t Veer P, Kromhout D (1998) Dietary intake of antioxidant (pro)-vitamins, respiratory symptoms and pulmonary function: the MORGEN study. Thorax 53: 166-171.
Schünemann HJ, Grant BJ, Freudenheim JL, Muti P, Browne RW, et al. (2001) The relation of serum levels of antioxidant vitamins C and E, retinol and carotenoids with pulmonary function in the general population. Am J Respir Crit Care Med 163: 1246-1255.
Tabak C, Arts IC, Smit HA, Heederik D, Kromhout D (2001) Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study. Am J Respir Crit Care Med 164: 61-64.
Black PN, Scragg R (2005) Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination survey. Chest 128: 3792-3798.
Guénégou A, Leynaert B, Pin I, Le Moël G, Zureik M, et al. (2006) Serum carotenoids, vitamins A and E, and 8 year lung function decline in a general population. Thorax 61: 320-326.
Rizwan Ul Hasan, Pranav Prabhat, Kausar Shafaat, Rizwana Khan, Phytochemical Investigation And Evaluation of Antioxidant Activity of Fruit of Solanum indicum Linn. International Journal of Pharmacy and Pharmaceutical Sciences, 2013, Vol 5, Issue 3, 237-242
Prabhu Ashwini,Krishnamoorthy M, Antioxidant Activity Of Ethanolic Extract of Cassia tora L, International Journal of Research in Ayurveda and Pharmacy 2011,2(1), 25-252
Santosh Kumar Nagalapur And S. Paramjyothi, In Vitro Antioxidant Activity Of Launaea pinnatifida Cass Leaves, The bioscan 2010, 5 (1) :105 - 108
N. Praveen1, M. Thiruvengadam, H. J. Kim1, J. K. Praveen Kumar and I. M. Chung, Antioxidant activity of Tinospora cordifolia leaf extracts through non-enzymatic method, Journal of Medicinal Plants Research Vol. 6(33):4790-4795,
Mallika Jainu and C.S. Shyamala Devi, Antioxidant Effect Of Methanolic Extract Of Solanum nigrum Berries On Aspirin Induced Gastric Mucosal Injury, Indian Journal of Clinical Biochemistry, 2004, 19 (1) 57-61
S. Patel , T. Patel , K. Parmar , B. Patel , and P. Patel, Evaluation Of Antioxidant Activity, Phenol And Flavonoid Contents of Momordica charantia Linn. Fruit, ARPB, 2011; Vol 1(2), 120-129
Laxmi Ahirwal, Siddhartha Singh, Manish Kumar Dubey, Vandana Bharti and Archana Mehta, Investigation of Antioxidant Potential of Methanolic Extract of Swertia chirata Buch. Ham. European Journal of Medicinal Plants 2014, 4(11): 1345-1355
Patel Diti I., Patel Disha I., Shah Vaishali N., Preliminary Phytochemical Screening And Evaluation Of Free Radical Scavenging Activity Of Luffa acutangula Var Amara Fruit, International Journal of Pharmaceutical Erudition, 2012, 2(1), 34-41
Helen A, Rajasree CR, Krishnakumar K, Augusti KT, Vijayammal PL. Antioxidant role of oils isolated from garlic (Allium sativum Linn) and onion (Allium cepa Linn) on nicotine-induced lipid peroxidation, Vet Hum Toxicol. 1999 Oct;41(5):316-9.
Mohammad Akbar Dar and Mubashir Hussain Masoodi, Evaluation of antioxidant activity of Portulaca oleracea Linn. from Kashmir Himalaya, Nat Prod Chem Res 2014, Volume 2, Issue 5, 222
Mijanur Rahman, Shahdat Hossain, Asiqur Rahaman, Nusrat Fatima, Taslima Nahar et al., Antioxidant Activity of Centella asiatica (Linn.) Urban: Impact of Extraction Solvent Polarity, Journal of Pharmacognosy and Phytochemistry, Vol. 1 No. 6, 27-32
M. Badrul Alam, M. Sarowar Hossain, N. Sultana Chowdhury, M. Asadujjaman, Ronok Zahan, Antioxidant, Anti-inflammatory and Anti-pyretic Activities of Trichosanthes dioica Roxb. Fruits, Journal of Pharmacology and Toxicology, 2011, Volume: 6, Issue: 5; 440-453
G H Urmila, B Ganga Rao, T Satyanarayana Phytochemical And In-Vitro Antioxidant Activity Of Methanolic extract Of Lactuca scariola&Celosia argentea Leaves. Journal of Drug Delivery and Therapeutics, Vol 3, No 4 (2013)
Namrata k. Satam, lavu s. Parab, suvarna i. Bhoir, HPTLC Finger Print Analysis And Antioxidant Activity Of Flavonoid Fraction Of Solanum melongena Linn Fruit, International Journal of Pharmacy and Pharmaceutical Sciences, 2013, Vol 5, Issue 3, 734-740
Passali D, Lauriello M, Mezzedimi C, Bellussi L. Nasal allergy and atmospheric pollution. Int J Pediatr Otorhinolaryngol. 1999; 49:257-60.
Salib RJ, Drake-Lee A, Howarth PH. Allergic rhinitis: past, present and the future. Clin Otolaryngol 2003; 28: 291-303.
Nirmal SA, Patel AP, Bhawar SB, Pattan SR. Antihistaminic and antiallergic actions of extracts of Solanum nigrum berries: possible role in the treatment of asthma. J Ethnopharmacol. 2012 Jun 26;142(1):91-7.
Choi JR, Lee CM et al apigenin protects ovalbumin induced asthma through the regulation of GATA3 gene , Inter Immuno (1009)918-924
Maharudra S Rakh, Amol N Khedkar, Nilesh N Aghav, Sanjay R Chaudhari, Antiallergic and analgesic activity of Momordica dioica Roxb. Willd fruit seed, Asian Pacific Journal of Tropical Biomedicine (2012)S192-S196
G.Sreejith, PG Latha et al anti allergic, anti-inflammatory and anti-lipid peroxidant effect of Cassia oxidentalis Linn. Indian journal of experimental biology Vol. 48 , May 2010 pp. 494-498
Mathew George, Lincy Joseph, and Ramaswamy, Anti-Allergic, Anti-Pruritic, and Anti-Inflammatory Activities of Centella Asiatica Extracts Afr J Tradit Complement Altern Med. 2009; 6(4): 554–559.
Paliwa JK, Dwivedi AD, Sihgh S, Gupta RC. Pharmacokinetics and in-situ absorption studies of a new anti-allergic compound 73/602 in rats. Int J Pharm 2000; 197(1-2):213-20.
Wagner H. Search for new plant constituents with potential antiphlogistic and antiallergic activity. Planta Med 1989; 55(3):235-41.
K D Tripathi, Essentials of Medical pharmacology, Jaypee brothers Medic al publishers pvt Ltd, New Delhi, 6th edition, 2008:214
Rang HP, Dale MM, and Ritter JM. Pharmacology. Churchill Livingstone, New York, 1999
Mohammad Taher Boroushaki , Mohammad Hosein Boskabady , Farhad Malek, ,Antitussive effect of Portulaca oleracea L. in guinea pigs, Iranian Journal of Pharmaceutical Research (2004) 3: 187-190
Raja Chakraborty, Biplab De, N. Devanna, and Saikat Sen Antitussive, expectorant activity of Marsilea minuta L., an Indian vegetable J Adv Pharm Technol Res. 2013 Jan-Mar; 4(1): 61–64.
Dhuley JN. Antitussive effect of Adhatoda vasica extract on mechanical or chemical stimulation-induced coughing in animals. J Ethnopharmacol. 1999 Nov 30;67(3):361-5.
Iyekowa O, Uzama-Avenbuan O, Edema MO, Enadeghe OR and Odaro SI. Antiasthmatic activity of Portulaca oleracea. Linn. Sky Journal of Biochemistry Research. 2012; 1 (1): 1-6.
Raja Chakraborty, Biplab De, N. Devanna, and Saikat Sen Antitussive, expectorant activity of Marsilea minuta L., an Indian vegetable J Adv Pharm Technol Res. 2013 Jan-Mar; 4(1): 61–64.
Journal of Ayurveda and Integrated Medical Sciences (JAIMS) retains the copyright of the contents of this journal but grant the readers the right to use the contents with terms and conditions under a creative common attribution licenses 4 of Attribution, Share Alike and Non-commercial type (CC BY-NC-SA) that allows copy, distribute, display, and perform the work and make derivative works based on it only for non-commercial purposes.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.