A review on Mundi (Sphaeranthus indicus Linn) - Its medicinal value in Hypothyroidism

Abstract

Thyroid dysfunctions are the most common endocrine abnormalities of which major ones are hypothyroidism and hyperthyroidism. Hormone replacement therapy has been a standard approach to thyroid dysfunction. However, herbal approach to treatment of thyroid dysfunction is gaining popularity as it is said to be equally effective, safe and devoid of any side effects. The synthesis and transport of thyroid hormones play a vital role in the normal physiology and functioning of thyroid hormones. HPT axis with its negative feedback mechanism helps in maintaining normal hormone levels. The level of TSH is the primary indicator of hypothyroidism and a thorough evaluation is needed to know the pathology behind before starting hormone supplementation therapy. Hashimoto’s Thyroiditis and Autoimmune Thyroiditis are the two main pathogenesis involved in the manifestation of hypothyroidism. While analysing the signs and symptoms of hypothyroidism in Ayurvedic view, It can be understand with the involvement of all Srotas. The Kaphadosha and Vatadosha Vruddhi is elicited and Pitta Doshakshaya is seen. Though some physicians consider it as a Sthanikavyadhi under Galagandaroga, it’s Dushti Lakshanas are seen in whole body. Ayurvedic system of medicine has been very effective in maintenance and treatment of hypothyroiditis. Mundi (Sphaeranthus indicus Linn) is one such drug which is endowed with properties like Gandanashini, Vatasleshmahara, Agnikruth and Rasayana. This review aims at providing comprehensive information regarding Mundi (Sphaeranthus indicus Linn) used in Ayurveda acting towards correction of thyroid dysfunction.