Concept of Santarpana: A Scientific Analysis
Abstract
Human beings are the supreme creature in the universe they have the power to solve all problems including diseases. Acharya Charaka has explained in Charaka Samhita about the treatment protocol of the different type of life styles disorders considering to their pathogenesis. Santarpana is the one type of treatment procedures among all. If one does not maintain the proper protocol of Santarpana Ahara (dietetics) and Vihara (daily routine) then it vitiates Kapha, Mamsa and Meda, which cause various over nutritive disorders, which are popularly known as life style disorders. So, Santarpana acts as a Hetu (causative factors) and type of Chikitsa (treatment) depending upon the improper and proper use Santarpana is also responsible for maintaining the normal physiology of homeostatic process through energy balance by the intake of Santarpana Ahara and Vihara. Body weight is regulated through the energy balance, the amount of energy (ingested fuels as food) intake and the amount of energy expenditure (muscle action) over an extended period of time. In homeostatic conditions all ingested energies are normally metabolized to maintain basal metabolic rate, thermogenesis, and muscle action. Excess ingested energies are stored as fat in adipocyte for using later as per body need. To maintain basal metabolic rate (BMR) Agni (power of digestion and metabolism) plays an important role. Basically, Santarpanaja Vyadhi in terms of obesity is characterized by a dysregulation of the neuro-physical signals that controls the food intake, inducing an imbalance between energy expenditure and energy intake. A complex network of peripheral and hypothalamic signals helps to balance between food intake, nutritional partitioning or body weight, energy homeostasis and body’s homeostasis. Leptin and ghrelin are two hormones that have a major influence on energy balance. Therefore, this review attempt to shed light on the role of Santarpana in terms of ghrelin and leptin to maintain the Dhatusamya (body’s homeostasis) through regulation of the energy intake and expenditure along with BMR of human body and which will be helpful for scholars in treatment of diseases and advising precautions.
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2. Lenard NR, Berthoud HR. Central and peripheral regulation of food intake and physical activity: pathways and genes. Obesity (Silver Spring, Md). 16 Suppl 3(Suppl 3), S11–S22. https://doi.org/10.1038/oby.2008.511.
3. Castañeda TR, Tong J, Datta R, Culler M, Tschöp MH. Ghrelin in the regulation of body weight and metabolism. Front Neuroendocrinol. 2010;31(1):44-60. doi:10. 1016/j.yfrne.2009.10.008.
4. Lenard NR, Berthoud HR. Central and peripheral regulation of food intake and physical activity: pathways and genes. Obesity (Silver Spring, Md). 16 Suppl 3(Suppl 3), S11–S22. https://doi.org/10.1038/oby.2008.511
5. Klok MD, Jakobsdottir S, Drent ML. The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review. Obesity reviews: an official journal of the International Association for the Study of Obesity. 2007;8(1), 21–34.
6. Yolando Diz-Chaves. “Ghrelin, Appetite Regulation and Food Reward: Interaction with Chronic Stress”. International Journal of Peptides. vol-2011, article ID 898450, 11pages, 2011. http://doi.org/10.1155/2011/898450.
7. Woods SC, D'Alessio DA. Central control of body weight and appetite. The Journal of clinical endocrinology and metabolism. 93(11 Suppl 1), S37–S50. https://doi.org/10.1210/jc.2008-1630.
8. Lenard NR, Berthoud HR. Central and peripheral regulation of food intake and physical activity: pathways and genes. Obesity (Silver Spring, Md). 16 Suppl 3(Suppl 3), S11–S22. https://doi.org/10.1038/oby.2008.511.
9. Agnivesh. Caraka-Smhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta, By Yadavji Trikamji Ācārya. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra sthan-1, slok-24, p7.
10. Suśhrut. Sushrut Samhitā (Dalhan & Gayadas Tika) by Vaidya Yadav ji Trikam ji and Narayan Ram acarya. Chowkhamba Surbharti Prakashan, Varanasi. Reprint Edition 2012, Sutra-sthan-46, slok-42, p342.
11. Agnivesh. Caraka Smhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. By Yadavji Trikamji Ācārya. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra sthan-22, slok-6, p120.
12. M Monier Williams. A Sanskrit English Dictionary by Sir M. Monier Williams. Motilal Banarasi Das Publishers, Delhi. 1st Edition, reprint 1995;1899.
13. Agnivesh. Caraka-Smhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta By Yadavji Trikamji Ācārya. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-22, slok-9, p-388.
14. Agnivesh. Charaka-Samhita English Translation by Sharma R.K and Bhagwan Dash, Choukhambha Sanskrit Series Office, Varanasi. Volume- I, Sutra-sthan-22, slok-3,p400.
15. Agnivesh, Charaka-Samhita English Translation by Sharma R.K and Bhagwan Dash. Choukhambha Sanskrit Series Office, Varanasi. Volume I, Sutrasthan, 22, slok-14, p388.
16. Dr Kunte, Dr Navare. Vagbhat’s Aṣṭāng-Hridayam (Arundatta and Hemadri commentary). Chowkhamba Sanskrit Samsthan, Varanasi. Reprint 2010, Sutra sthan-16, slok -1, p246.
17. Patil SS, Kore AA. Conceptual study of Santarpana with special reference to its hetus. Ayurline: International Journal of Research in Indian Medicine. 2019;3(02).
18. Dr Kunte, Dr Navare. Vagbhat’s Aṣṭāng-Hridayam (Arundatta and Hemadri commentary). Chowkhamba Sanskrit Samsthan, Varanasi. Reprint 2010, Sutra sthan-16, slok-1, p-246;
19. Patil SS, Kore AA. Conceptual study of Santarpana with special reference to its hetus. Ayurline: International Journal of Research in Indian Medicine. 2019;3(02).
20. Patil SS, Kore AA. Conceptual study of Santarpana with special reference to its hetus. Ayurline: International Journal of Research in Indian Medicine. 2019;3(02).
21. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, nidan sthan-6, slok -4, p-445.
22. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, nidan sthan-6, slok -4, p-445.
23. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra sthan-6, slok -78-80, p-103.
24. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-27, slok-61-62, p- 157.
25. Patil SS, Kore AA. Conceptual study of Santarpana with special reference to its hetus. Ayurline: International Journal of Research in Indian Medicine. 2019;3(02).
26. Dr Kunte, Dr Navare. Vagbhat’s Aṣṭāng-Hridayam (Arundatta and Hemadri commentary). Chowkhamba Sanskrit Samsthan, Varanasi. Reprint 2010, Sutra sthan-19, slok -20-26, p-274.
27. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, chikitsa sthan, slok-4, p-445.
28. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, chikitsa sthan, slok-4, p-445.
29. Agnivesh. Charaka-Samhita, English Translation by Sharma R.K and Bhagwan Dash. Choukhambha Sanskrit Series Office, Varanasi. Volume- I, Nidana-sthan-4, slok-6, p55.
30. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-21, slok-36 &50, p-119.
31. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-5, slok-36 &50, p-119.
32. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-5, slok-88, p-46.
33. Patil SS, Kore AA. Conceptual study of Santarpana with special reference to its hetus. Ayurline: International Journal of Research in Indian Medicine. 2019;3(02).
34. Dr Kunte, Dr Navare. Vagbhat’s Aṣṭāng-Hridayam (Arundatta and Hemadri commentary). Chowkhamba Sanskrit Samsthan, Varanasi. Reprint 2010, Sutra sthan-14, slok-34, p-229.
35. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-23, slok-22-25, p-123.
36. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-22, slok-10, p-121.
37. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, viman-sthan-8, slok-89, p- 275.
38. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, Sutra-sthan-1 slok-28-30, p-7.
39. Agnivesh. Charak- Samhita, English Translation by Sharma R.K and Bhagwan Dash. Choukhambha Sanskrit Series Office, Varanasi. Volume- I, Sutra-sthan-22, slok-13, p-121.
40. Agnivesh, Yadavji Trikamji Ācārya (ed). Charaka-Samhita, Ayurveda Dipika Commentary of Sri Cakrapanidatta. Chowkhamba Sanskrit Sansthan, Varanasi. Reprint 2009, sarira-sthan, chapter-6, slok-14-16, p-332.
41. Agnivesh. Charaka-Samhita, English Translation by Sharma R.K and Bhagawan Dash. Choukhambha Sanskrit Series Office, Varanasi. Volume I, Sutra sthan-6, slok-15, p437.
42. Lenard NR, Berthoud HR. Central and peripheral regulation of food intake and physical activity: pathways and genes. Obesity (Silver Spring, Md). 2008;16.
43. Sujit K Choudhuri. ‘Metabolic Rate and Energy Expenditure’, Concise Medical Physiology. New Central Book Agency (P) LTD. 5th Edition, Chapter -VII, 2002;p343.
44. D Taylor, NPO Green, GW Stout, R Soper. ‘Heterotopic Nutrition’, Biological Science. Cambridge University Press, 3rd Edition, Chapter 8, 1998;p-252,291.
45. D Taylor, NPO Green, GW Stout, R Soper. ‘Heterotopic Nutrition’, Biological Science. Cambridge University Press, 3rd Edition, Chapter 8, 1998;p-252,291.
46. Eckstein, P. The Role of Ghrelin and Leptin in Obesity: Is Exogenous Administration of These Hormones a Possible Drug Therapy. The Science Journal of the Lander College of Arts and Sciences. 2011;4(2). Retrieved from https://touroscholar.touro.edu/sjlcas/vol4/iss2/7
47. Yolando Diz-Chaves. “Ghrelin, Appetite Regulation and Food Reward: Interaction with Chronic Stress”. International Journal of Peptides. vol-2011, article ID 898450, 11pages, 2011. http://doi.org/10.1155/2011/898450
48. Lafrenière J, Lamarche B, Laramée, C et al. Validation of a newly automated web-based 24-hour dietary recall using fully controlled feeding studies. BMC Nutri. 3, 34 (2017). https://doi.org/10.1186/s40795-017-0153-3.
49. Yolando Diz-Chaves. “Ghrelin, Appetite Regulation and Food Reward: Interaction with Chronic Stress. International Journal of Peptides. vol-2011, article ID 898450, 11pages, 2011. http://doi.org/10.1155/2011/898450.
50. Chrysi Koliaki, Alexander Kokkinos, Nicholas Tentolouris, Nicholas Katsilambros. "The Effect of Ingested Macronutrients on Postprandial Ghrelin Response: A Critical Review of Existing Literature Data". International Journal of Peptides. vol 2010, Article ID 710852, 9 pages, 2010. https://doi.org/10.1155/2010/710852.
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