A randomized controlled clinical study to evaluate the efficacy of Aragwadha Pushpa Lepa (Cassia fistula Linn.) in the management of Vyanga with special reference to Melasma

  • Nanditha M Final Year Post Graduate Scholar, Department of PG studies in Dravyaguna, Sri Sri College of Ayurvedic Science & Research, Bengaluru, Karnataka, India.
  • Mahesh C D Professor, Department of PG studies in Dravyaguna, Sri Sri College of Ayurvedic Science & Research, Bengaluru, Karnataka, India.
  • Seema Pradeep Professor & HOD, Dept. of PG studies in Dravyaguna, Sri Sri College of Ayurvedic Science & Research, Bengaluru, Karnataka, India.
Keywords: Aragwadha, Cassia fistula Linn., Chloasma, Melasma, Vyanga

Abstract

Vyanga is one of the Kshudraroga mentioned in the classics which are having Lakshana like Niruja, Tanu and Shyava Mandala. It can be correlated with Melasma in modern terms, which is also known as Chloasma. Melasma is an acquired pigmentary disorder, causing hyper-pigmented patches to appear on the facial skin. The prevalence varies between 1.5 % and 33.3 % in India. Female to male ratio in India is 4:1, indicating the high prevalence rate among females. Aragwadha Pushpa Churna along with Nimbuka Swarasa is applied over the hyper-pigmented patches in the condition of Vyanga in Cauvery river stretch of Namakkal district of Tamil Nadu as a folklore practice. A randomized clinical study was carried out to compare the efficacy with Varnya Gana Churna. The clinical study in the sample size of 30 was carried out in 2 groups with the intervention of Group A being Aragwadha Pushpa Churna Lepa and that of Group B being Varnya Gana Churna Lepa, with 30 days of drug application period and 15 days of drug-free follow up period. Differential diagnosis was ruled out with the help of Wood’s lamp. Assessment was done with the help of criterias like Amount of discolouration, Arbitrary grading and Area of the lesion. Various statistical tests like Parametric, Non-parametric, Friedman repeated measures ANOVA on ranks, etc. were carried out to analyse the results of the study. Both Aragwadha Pushpa Churna and Varnya Gana Churna have significant effect in the management of Vyanga with special reference to Melasma. When improvement in the individual criteria was compared, Aragwadha Pushpa Churna showed better results in reducing the amount of discolouration & the number of lesions. Whereas, Varnya Gana Churna showed better results in reducing area of the lesion.

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References

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CITATION
DOI: 10.21760/jaims.8.12.1
Published: 2024-01-31
How to Cite
MN., C DM., & PradeepS. (2024). A randomized controlled clinical study to evaluate the efficacy of Aragwadha Pushpa Lepa (Cassia fistula Linn.) in the management of Vyanga with special reference to Melasma. Journal of Ayurveda and Integrated Medical Sciences, 8(12), 01 - 07. https://doi.org/10.21760/jaims.8.12.1
Section
Original Article