An Invitro study to evaluate the Krimighna Karma (Antimicrobial Activity) of Dugdhika Patra (Euphorbia hirta Linn.) against Staphyloccus aureus

Prajwal C R; Nisarga K S; Pradeep; Anuradha K N

doi:10.21760/jaims.9.10.5

Prajwal C R Post Graduate Scholar, Dept. of Dravyaguna, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.
Nisarga K S Post Graduate Scholar, Dept. of Dravyaguna, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.
Pradeep Associate Professor, Dept. of Dravyaguna, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.
Anuradha K N Assistant Professor, Dept. of Dravyaguna, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.

DOI: https://doi.org/10.21760/jaims.9.10.5

Keywords: Dugdhika, Krimighna, Swarasa, Staphylococcus aureus, Zone of inhibition, Antibacterial

Abstract

Background: Today’s world’s mortality rate depends on the infectious diseases and accounts for about 50% of all deaths. Deadly diseases of this century were mainly caused by bacterial infections. Biologically important plants were discovered by evaluation of ethnopharmacological data and they are locally populated with immediate therapeutic action. The recognition of any of the Dravya is through its Karma (Action). The Karma is mainly explained with the help of Rasa Panchaka in science of Ayurveda. Krimighna Karma is one such Karma which is responsible for the destruction of the Krimi. The plant Dugdhika is widely used in traditional medicine to cure various diseases, especially gastrointestinal disorders, respiratory disorders and skin disorders. Aim: To evaluate the Krimighna Karma of Dugdhika Patra Swarasa against Staphylococcus aureus bacteria. Materials and Methods: In this study, Dugdhika Patra (Euphorbia hirta Linn.) Swarasa was evaluated for its antibacterial activity against Staphylococcus aureus bacteria using well diffusion method. Observations and Results: The zone of inhibition was observed through agar well diffusion method. Swarasa had shown maximum Zone of inhibition (9mm) for Staphylococcus aureus bacteria when dispensed directly and moderate zone of inhibition (6mm) with diluted concentration after 24 hours of incubation period when compared to control group but not as that of standard group. These findings established the potential of Dugdhika Patra Swarasa has effective antibacterial agent against Staphylococcus aureus. However, further studies are needed to evaluate the active compounds and probable medicinal benefits in humans by clinical trials.

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