An open label single arm prospective clinical study on the combined effectiveness of Panchanimbakam Churna Vati and Pathyadi Lepa in Kitibha Kushta (Psoriasis)

Kalpana Bhamini; Lakshmiprasad L. Jadhav; Rajouri Joshi

doi:10.21760/jaims.7.7.5

Kalpana Bhamini Post Graduate Scholar, Department of PG Studies in Kayachikitsa, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.
Lakshmiprasad L. Jadhav Professor, Department of Kayachikitsa, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.
Rajouri Joshi Post Graduate Scholar, Department of PG Studies in Kayachikitsa, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India

DOI: https://doi.org/10.21760/jaims.7.7.5

Keywords: Kitibha Kushta, Psoriasis, Panchanimbakam Churna Vati, Pathyadi Lepa

Abstract

Kitibha Kushta is mentioned under Kshudra Kushta and is one among the Ashtamahagada. There is the involvement of Tridosha in all Kushta but the predominance of Dosha makes the types & manifestations of Kushta different. Psoriasis is one of the most common skin disorders. It is a papulosquamous disorder of the skin characterized by sharply defined erythematosquamous lesions. It is chronic and is well known for its course of remission and exacerbation. Prevalence of psoriasis in adults varies from 0.44 to 2.8%, with a much lower prevalence in children. The combined formulations Panchanimbakam Churna Vati and Pathyadi Lepa, mentioned in Gadanigraha and Yogaratnakara respectively, are indicated for the management of Kitibha Kushta. The combination collectively contains Kushtaghna Dravyas and has Katu, Tikta and Kashaya Rasa, Laghu, Ruksha Guna, and Ushna Veerya that are helpful in Samprapti Vighatana of Vata and Kapha dominant Kushta. Material and Methods: Among 30 registered participants, 25 completed the treatment. They were administered with Panchanimbakam Churna Vati orally 3 gm per day before food and Pathyadi Lepa externally for 30 days. The Lakshanas and PASI score was assessed on the 1^st, 15^th, and 30th. For Statistical analysis, subjective parameters were assessed by Cochran’s Q test followed by McNemar test, and objective parameters were assessed by Repeated Measures Anova and Paired T-Test. Results: There was a statistically significant improvement in the signs and symptoms of Kitibha Kushta (Psoriasis)(p<0.05). Conclusion: The combination of Panchanimbakam Churna Vati and Pathyadi Lepa, is effective in the management of Kitibha Kushta (Psoriasis)

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