Ayurveda Practitioners Consensus to Develop Strategies for Prevention and Treatment of Corona Virus Disease (COVID-19)

  • Dr. Ashok Kumar Panda Research Officer, Central Ayurveda Institute for Hepatobiliary Disorders, CCRAS, Ministry of AYUSH, Govt. of India, Bhubaneswar, Odisha, INDIA.
  • Amit Kumar Dixit Assistant Director (Biochemistry), Central Ayurveda Research Institute for Drug Development, CCRAS, Kolkata, INDIA.
  • Suvendu Rout Head, Department of Kayachikitsa, SJS Ayurveda College, Nazrathpet, Chennai, INDIA.
  • Baidyanath Mishra Director (R&D), Ingex Germany GmBH, Theodor-Heuss-Allee Business Center GmbH. Theodor-HeussAllee 112, 60486 Frankfurt am Main, Germany,
  • Umesh V. Purad Principal, DGM Ayurveda Medical College Cum Post Graduation Centre and Hospital, Gadag, Karnataka, INDIA.
  • Sarbeswar Kar Medical Superintendent, SDM Institute of Ayurveda and Hospital, Anchepalya, Bangalore, Karnataka, INDIA.
Keywords: Corona, COVID-19, Pathogenesis, Consensus, Rasayana

Abstract

Background: The outbreak of Coronavirus disease (COVID-19) has been recently declared as Public Health Emergency of International Concern (PHEIC) by World Health Organization and the virus has now spread beyond the boundaries of countries and continents. At present, no specific antiviral treatment or vaccine is available or recommended to counter the COVID-19, and the potential therapy is still symptomatic. Objective: The primary aim of the study is to review ancient classical literatures and past human treatment protocols of Ayurveda for prevention and treatment of infectious diseases and flu like illnesses, so as to provide guidance for the prevention of COVID-19. Methods: Classical Ayurveda and recent modern literature with treatment protocols of Ayurveda for prevention and treatment of flu and infectious diseases were reviewed and COVID-19 has been categorized in four specific situations based on the severity of clinical condition. Total 110 Ayurveda practitioners of different parts of India were participated in the survey. These specific situations were conveyed and described to these participants and their opinions and options were collected through social media platform i.e. WhatsApp or SMS. Results: Recommendation and suggestions received from more than 50% participants were taken into accounts to draft the recommendation for probable preventive and therapeutic regimen for the disease. Conclusion: The results obtained in the study may provide a preventive strategy to the Ayurveda practitioners as well as common people across the globe by increasing the innate immunity of the body to combat COVID-19. However, till today, social distancing is considered as most effective way to stop the spread of COVID-19. Further, pilot study for different group is recommended.

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References

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al., Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet, 395 (10223) (2020), 497–506.

Nishiura H, Jung SM, Linton NM, Kinoshita R, Yang Y, Hayashi K, et al., The extent of transmission of novel coronavirus in wuhan, China, 2020, J Clin Med (2020), 9.

Bassetti M, Vena A, Roberto Giacobbe D. The Novel Chinese Coronavirus (2019-nCoV) Infections: challenges for fighting the storm, Eur. J Clin Invest (2020)e13209.

Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al., First case of 2019 novel coronavirus in the United States, N Engl J Med (2020).

Jaimes JA, Millet JK, Stout AE, Andre NM, Whittaker GR. A tale of two viruses: the distinct spike glycoproteins of feline coronaviruses, Viruses 12 (2020).

Lu R, Zhao X, Li, Niu P, Yang B, Wu H, et al., Genomic characterisation andepidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding, Lancet 395 (10224) (2020) 565–574.

Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS, J. Virol. (2020).

Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, et al., Remdesivir and Chloroquine effectively Inhibit the Recently Emerged Novel Coronavirus (2019-nCoV) in Vitro, Cell research, (2020).

Toots M, Yoon JJ, Cox RM, Hart M, Sticher ZM, Makhsous N, et al., Characterization of orally efficacious influenza drug with high resistance barrier inferrets and human airway epithelia, Sci. Transl. Med. (2019) 11.

Traditional Chinese medicine plays an important role in epidemic control. https://www.alwihdainfo.com/ Traditional-Chinese- Medicine-plays-important-role-inepidemic-control_a83224.html.

TCM plays key role in containing epidemics in Chinese history. http://global.chinadaily.com.cn/a/202004/01/WS5e83 c469a3101282172836e7.html.

Song Y, Yao C, Yao Y, Han H, Zhao X, Yu K, et al., XueBiJing Injection Versus Placebo for Critically Ill Patients With Severe Community-Acquired Pneumonia: A Randomized Controlled Trial, Crit Care Med. (2019) Sep;47(9):e735-e743.

AYUSH Advisory for Prevention of Corona virus Infections useful in symptomatic management of Corona Virus infection –released on 29 JAN 2020 10:29AM by PIB Delhi.

Panda AK. Current status of Infectious diseases in Ayurveda, Ayursurabhi- (2005), 66-67.

Charak Samitha Agnivesa’s treatise refined and annoted by Charak and redacted by Dridhabala. Translator by Prof. Priyavrat Sharma Vol.II Talawar UJAHM (2015), 03 (04): 109-111.

Mamidi P, Gupta K. Sama Sannipata Jwara- Sepsis, Sirs, Mods, Septic Shock and Delirium. Int J Complement Alt Med (2017), 8(2): 00257.

Susruta Samhita- Uttara tantra, Symptoms and Treatment of Fever (Jvara) by by Kaviraj Kunja Lal Bhishagratna (1916).

Asthang Hridaya by Dr.Ganesha Gadre, Raghuvanshi Prakashana, Chikitsa Sthana 1/ Edition (1996), 3.

Madhavakara Madhava nidaana with Sanskrit commentary ‘Madhukosha’ by Vijayarakshita and Shrikanthadatta. Vol 1. Jwara nidaana adhyaya, 2/18- 23. In: Dr Brahmananda Tripathi & Chaukhamba surbharati prakashan (Eds.), Varanasi, India, (2012) pp. 111-120.

Kashyapa Samhita, Chikitsasthana, KrimiChikitsa, vidyotinihindi commentary, Bhishgacharya SS. Varanasi: ChakhambhaSansthan; (2004).

Carrasco FR, Schmidt G, Romero AL, Sartoretto JL, Caparroz-Assef SM, Bersani-Amado CA, Cuman RK. Immunomodulatory activity of Zingiber officinale Roscoe, Salvia officinalis L. and Syzygium aromaticum L. essential oils: evidence for humor- and cell-mediated responses. J Pharm Pharmacol. (2009), 61(7):961-7.

KIM SH, Lee YC, Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumininduced asthma model. J Pharm Pharmacol. (2009), 61(3):353-9.

Bui TT, Fan Y, Piao CH, Nguyen TV, Shin DU, Jung SY, et al., Piper Nigrum extract improves OVA-induced nasal epithelial barrier dysfunction via activating Nrf2/HO-1 signaling. Cell Immunol. (2019), 30:104035.

Wang K, Conlon M, Chen BB, Bączek T, Natural products –antargeted modulators of Immuno system, Journal of Immunology Research, (2018

Sordillo PP, Helson L, Curcumin Suppression of Cytokine Release and Cytokine Storm. A Potential Therapy for Patients with Ebola and Other Severe Viral Infections, In Vivo International Journal of Experimental and Clinical Pathophysiology and Drug Research, (2015), 29:(1-4).

Sharma R, Martins N, Kuca K, Chaudhary A, Kabra A, Rao MM, et al., Chyawanprash: A Traditional Indian Bioactive Health Supplement, Biomolecules. (2019) May; 9(5):161.

Singh B, Gupta V, Bansal P, Kumar D, Murali Krishna C. Pharmacological Potential of Polyherbal Formulation, Sudarshan Churna – A Review. International Journal of Ayurvedic Medicine, (2011), 2(2), 52-61.

Desai VR, Ramkrishnan R, Chintalwar GJ, Sainis KB. G1- 4A, an immune-modulatory polysaccharide from Tinospora cordifolia, modulates macrophage responses and protects mice against lipopolysaccharide induced endotoxic shock. Int. Immunopharmacol. (2007), 7: 1375-1386

Sachan S, Dhama K, Latheef SK, et al. Immunomodulatory Potential of Tinospora cordifolia and CpG ODN (TLR21 Agonist) against the Very Virulent, Infectious Bursal Disease Virus in SPF Chicks. Vaccines (Basel). (2019), 7(3):106.

Walunj MB, Ankush Gunjal, Patgiri B J, Prajapati P K, Critical review of Vasanta Malati Rasa - A Herbomineral Product, International Journal of Ayurveda Medicine, (2014), 5(3),244-253.

Hiremath V, Hiremath B. S, Mohapatra S, Das A. K. Literary Review of Parijata (Nyctanthus Arbor-Tristis Linn.) An Herbal Medicament with Special Reference to Ayurveda and Botanical Literatures. Biomed Pharmacol J (2016), 9(3).

Saxena RS, Gupta B, Saxena KK, Srivastava VK, Prasad DN. Analgesic, antipyretic and ulcerogenic activity of Nyctanthes arbor tristis leaf extract. J Ethnopharmacol (1987), 19 (2):193-200.

Kumari P, Sahal D, Jain SK, Chauhan VS. Bioactivity guided fractionation of leaves extract of Nyctanthes arbor tristis (Harshringar) against P falciparum. PLoS One. (2012), 7(12):e51714.

Das SK, Chandra A, Agrawal SS and Singh N, 1983. Ocimum sanctum (tulsi) in the treatment of viral encephalitis. The Antiseptic, (1983), pp: 1-5

CITATION
DOI: 10.21760/jaims.v5i01.821
Published: 2020-02-29
How to Cite
Dr. Ashok Kumar Panda, Amit Kumar Dixit, Suvendu Rout, Baidyanath Mishra, Umesh V. Purad, & Sarbeswar Kar. (2020). Ayurveda Practitioners Consensus to Develop Strategies for Prevention and Treatment of Corona Virus Disease (COVID-19). Journal of Ayurveda and Integrated Medical Sciences, 5(01), 98-106. https://doi.org/10.21760/jaims.v5i01.821
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Original Article