Multiple sclerosis an Ayurvedic approach - A Critical View

Abstract

Autoimmune disease occurs when the immune system attacks self-molecules as a result of a breakdown of immunologic tolerance to autoreactive immune cells. Autoimmune disorders are on the rise globally and affect 8.5% of the population worldwide. Multiple sclerosis (MS), the most prevalent neurological disability is an autoimmune disease of Central nervous system characterized by chronic inflammation, demyelination, gliosis and neuronal loss. Although the aetiology and pathogenesis of MS remains unclear, several studies illustrate that the cause of MS is multifactorial and include genetic predisposition together with environmental factors. Therapies for MS are based on the use of antiinflammatory and immunomodulatory drugs, but these treatments are not able to stop the destruction of nerve tissue. Hence a comprehensive management programme is strongly recommended for all patients with multiple sclerosis, enhancing health-related quality of life through advocating wellness, addressing aggravating factors, and managing comorbidities. Multiple Sclerosis can be understood as anuktavata vyadhi based on similarity of symptoms as there is no direct correlation in Ayurvedic classics. With immunosuppressant or cortico-steroids as only available treatment in modern sciences, Ayurveda can be ray of hope. The scope of Ayurvedic Management and preventive aspects mainly concentrates on improving the quality of life and decrease dependency by patients on others. Hence here an attempt is made to analyse the disease and its management.