Study of Antidotal Effect of Saindhavadi Yoga in Jayapala Beeja poisoning in Albino Mice

  • Supriya H. Sakhare Assistant Professor, Dept. of Agada Tantra, SSVP Ayu. College, Hingoli, Maharastra, India.
  • Balasaheb D. Gaikwad Assistant Professor, Dept. of Kriya Sharira, SSVP, Ayurveda College, Hingoli, Maharastra, India.
Keywords: Jayapala, Croton Tiglium, Saindhvadi Yoga

Abstract

Accidental poisoning of Jayapala occurs due to ingestion of oil or overdose of medicinal preparations which contains Jayapala. It is also used as abortificant, roots may also be locally used for abortion. LD50 value of Jayapala Beeja Churna was calculated according to OECD guidelines. Drug safety of Saindhavadi Yoga was also done to see whether it was toxic or not. Then dose of both drugs were calculated. In vivo study was conducted at authentified animal house. After dosing the animals with suspension of Jayapala Beeja Churna, they are observed for symptoms of poison. All necessary precautions were taken during experiment. Observations were tabulated, Data was analysed with the help of descriptive statistics along with Mann-whiteny U test for statistical significance at p value of 0.05 and ANOVA test. Conclusion was drawn based on the analysed data that shows role of Saindhvadi Yoga as antidote against Jayapala Beeja poisoning. The observations confirmed that, Saindhvadi Yoga delays the effect of Jayapala Beeja poisoning. It shows, there is a difference in experimental (Group-II) and trial group (Group-III).

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CITATION
DOI: 10.21760/jaims.v2i1.7493
Published: 2017-02-28
How to Cite
Supriya H. Sakhare, & Balasaheb D. Gaikwad. (2017). Study of Antidotal Effect of Saindhavadi Yoga in Jayapala Beeja poisoning in Albino Mice. Journal of Ayurveda and Integrated Medical Sciences, 2(01), 92-97. https://doi.org/10.21760/jaims.v2i1.7493
Section
Original Article