Study of Antidotal Effect of Saindhavadi Yoga in Jayapala Beeja poisoning in Albino Mice
Abstract
Accidental poisoning of Jayapala occurs due to ingestion of oil or overdose of medicinal preparations which contains Jayapala. It is also used as abortificant, roots may also be locally used for abortion. LD50 value of Jayapala Beeja Churna was calculated according to OECD guidelines. Drug safety of Saindhavadi Yoga was also done to see whether it was toxic or not. Then dose of both drugs were calculated. In vivo study was conducted at authentified animal house. After dosing the animals with suspension of Jayapala Beeja Churna, they are observed for symptoms of poison. All necessary precautions were taken during experiment. Observations were tabulated, Data was analysed with the help of descriptive statistics along with Mann-whiteny U test for statistical significance at p value of 0.05 and ANOVA test. Conclusion was drawn based on the analysed data that shows role of Saindhvadi Yoga as antidote against Jayapala Beeja poisoning. The observations confirmed that, Saindhvadi Yoga delays the effect of Jayapala Beeja poisoning. It shows, there is a difference in experimental (Group-II) and trial group (Group-III).
Downloads
References
Bramhanand Tripathi. Charaka Samhita. Sutrasthana 24/60. Chaukhamba Prakashana, Varanasi, 2009;p.47.
Ambika Dutta Shastri. Sushruta Samhita. Kalpasthana 2/3, Chaukhamba Prakashana, Varanasi, 2009
Sadananda Sharma. Rasatarangini. 11th ed. New Delhi: Motilal Banarsidas Publishers; 1982;p.201
Jaising P. Modi, B.V. Subrahmanyam. Modi’s Jurisprudence and Toxicology. 21st edition. 2002;628
Vaidya Shri Laxmipati Shastri, Yoga Ratnakar, Caukhamba Prakashana, Varanasi, 2010.
B.K. Mahajan, Methods in Bio-Statistics, Jaypee Brothers Medical Publishers, New Delhi, 7th Edition, reprint 2010.
MGI — Biology of the Laboratory Mouse". Informatics.jax.org. Retrieved 2010-07-29.
Laboratory mice -Wikipedia, the free encyclopedia.
Measuring motor coordination in mice, Robert M.j Deacon, dept. experimental psychology university of oxford, science education.
Journal of Ayurveda and Integrated Medical Sciences (JAIMS) retains the copyright of the contents of this journal but grant the readers the right to use the contents with terms and conditions under a creative common attribution licenses 4 of Attribution, Share Alike and Non-commercial type (CC BY-NC-SA) that allows copy, distribute, display, and perform the work and make derivative works based on it only for non-commercial purposes.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.